About Syndromes
Healthcare professionals use the word syndrome to describe a set of symptoms that tend to appear together under similar circumstances and respond to certain treatments.
Lennox-Gastaut syndrome, for example, is one of the most severe forms of epilepsy; it accounts for up to 10% of all cases of childhood epilepsy. It usually develops in children between 1 and 8 years of age, with 3 the average age of onset.2 (For more, see our Web page About Lennox-Gastaut Syndrome.
Diagnosis
People who have at least two unprovoked seizures that occur at different times have a seizure disorder. A diagnosis is made based on the person's history and the observations of eyewitnesses. Seizures may be suspected if symptoms such as loss of consciousness, muscle spasms that shake the body, loss of bladder control, sudden confusion, and an inability to pay attention occur. However, true seizures are much less common than most people think; most episodes of brief unconsciousness are more likely to be fainting (syncope (see Low Blood Pressure: Fainting).
An eyewitness report of the episode can be very helpful to doctors. An eyewitness can describe exactly what happened, whereas the person who had the episode usually cannot. An accurate description of the circumstances is needed: how fast the episode started; whether it involved abnormal muscle movements (such as spasms of the head, neck, or facial muscles), tongue biting, or loss of bladder control; how long it lasted; and how quickly the person recovered. Doctors also need to know what the person experienced before the episode: whether the person had a premonition or warning that something unusual was about to happen and whether anything, such as certain sounds or flashing lights, seemed to trigger the episode.
To help diagnose a seizure disorder, doctors use electroencephalography (EEG), a painless, safe procedure that records electrical activity in the brain (see Diagnosis of Brain, Spinal Cord, and Nerve Disorders: Electroencephalography). Doctors examine the recording (electroencephalogram) for evidence of abnormal electrical discharges. Because abnormal discharges are more likely to occur after too little sleep, EEG is sometimes scheduled after a person has been deprived of sleep for 18 to 24 hours. Even if a seizure did not occur during EEG, abnormalities may be present. Because of the limited recording time, EEG can miss abnormalities and the electroencephalogram may appear normal, even in people who have a seizure disorder.